Alcohol-related hepatocellular carcinoma (ALD-HCC) is, in Europe, the leading cause of liver cancer. This study aims to identify novel susceptibility loci for the development of HCC in people with alcohol related cirrhosis (ARC). Design: Patients with ARC and HCC (cases) and controls with ARC but without HCC, will be included in a two-stage genome-wide association study. Then a meta-analysis of SNPs present in both cohorts (Pan-European + Fingenious) will be done.
